With "Sacanas Sem Lei", the filmmaker returned to dispute the Palme d'Or in 2009, but the prize was won by the Austrian filmmaker Michael Haneke with "The White Ribbon".
But "Inglourious Basterds" did not leave empty handed, since Christoph Waltz was chosen as the best actor and would win an Oscar a year later.
At the time, the participation of Tarantino was marked by the dance steps with the French actress Mélanie Laurent in the red carpet. In 2014, he repeated the scene with Uma Thurman, in celebration of the 20 years of "Pulp Fiction".
Many question whether he will dance this time with Margot Robbie, who plays Sharon Tate in "Once Upon a Time in … Hollywood." Either way, the glamor is guaranteed with the duo Leonardo DiCaprio and Brad Pitt, who work together for the first time.
On Tuesday morning, fans were already positioned in front of the historic Palais des Festivals in search of a coveted invitation to the screening.
I appeal against "spoilers"
The 165-minute film, filmed in 35mm, takes place in Los Angeles in 1969.
"Once Upon a Time …" follows the adventures of Rick Dalton (Leonardo DiCaprio), the TV western star, his double Cliff Booth (Brad Pitt) as well as his neighbor, actress Sharon Tate. Other famous figures, such as Bruce Lee and Steve McQueen, appear on the screen.
Little information was divulged about the ninth film of the director. "It's your most personal argument," one of the film's producers, David Heyman, told Entertainment Weekly magazine.
"In the film, there are memories of the child who grew up in Los Angeles and dreamed about Hollywood. It's really exciting because there's a lot of history in it."
With so many expectations, Tarantino, 56, has asked people to watch the film in Cannes not to reveal details.
A message shared on social networks on Monday began with "I Love Cinema. You love Cinema. It's the journey of discovering a story for the first time."
"I'm thrilled to be here in Cannes to share "Once Upon a Time … in Hollywood" with the festival crowd. The cast and crew worked hard to create something original, and I just ask that everyone avoid revealing anything that would prevent the following audience from experiencing the movie the same way. "Thank you."
Following the message on social networks came the hashtag #NoSpoilersInHollywood [nada de spoilers em Hollywood].
Tarantino will join the select group of filmmakers with two Golden Palms, alongside Bille August, Francis Ford Coppola, Luc and Jean-Pierre Dardenne, Michael Haneke, Shohei Imamura, Emir Kusturica and Ken Loach.